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1.
Georgian Med News ; (283): 89-96, 2018 Oct.
Article Ru | MEDLINE | ID: mdl-30516501

The aim of the study was to assess the impact of cytoflavin and bioflavin therapy on the dynamics of clinical and psychophysiological status of patients with Osteochondrosis. 150 patients with osteochondrosis of a backbone were investigated. The patients were divided into two groups using method of randomization: the main group - 75 patients - and control group -75 patients. All patients received a standard treatment (non-steroidal anti-inflammatory drugs, myorelaxants, chondroprotectors, as well as physiotherapy). The main group in addition to standard treatment received biofeedback therapy and cytoflavin. The results showed that cytoflavin and biofeedback therapy significantly enhanced the positive effect of standard treatment and significantly increased the quality of life of patients. It is recommended to treat elderly patients with neurological complications of spinal osteochondrosis with Cytoflavin in combination with biofeedback therapy Before prescribing biofeedback therapy and Cytoflavin it is necessary to take into account a number of positive and negative predictors of their effectiveness in reducing severity of pain syndrome.


Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Biofeedback, Psychology , Flavin Mononucleotide/therapeutic use , Inosine Diphosphate/therapeutic use , Nervous System Diseases/therapy , Niacinamide/therapeutic use , Physical Therapy Modalities , Spinal Osteochondrosis/therapy , Succinates/therapeutic use , Aged , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Combined Modality Therapy , Drug Combinations , Flavin Mononucleotide/administration & dosage , Humans , Inosine Diphosphate/administration & dosage , Middle Aged , Nervous System Diseases/drug therapy , Nervous System Diseases/psychology , Niacinamide/administration & dosage , Retrospective Studies , Spinal Osteochondrosis/drug therapy , Spinal Osteochondrosis/psychology , Succinates/administration & dosage , Surveys and Questionnaires , Treatment Outcome
2.
Adv Gerontol ; 30(4): 601-608, 2017.
Article Ru | MEDLINE | ID: mdl-28968038

We conducted a study of 150 patients on the basis of polyclinic № 91 in St. Petersburg. The effect of Cytoflavin and bio-inverse communication therapy on the dynamics of the condition of elderly patients with osteochondrosis was evaluated. A number of positive effects from such an addition to existing therapy, potentiating the nominal effect, were revealed.


Communication , Flavin Mononucleotide/pharmacology , Inosine Diphosphate/pharmacology , Niacinamide/pharmacology , Osteochondrosis/drug therapy , Succinates/pharmacology , Aged , Drug Combinations , Humans , Osteochondrosis/physiopathology , Osteochondrosis/psychology , Treatment Outcome
3.
Article Ru | MEDLINE | ID: mdl-28884718

AIM: To evaluate the efficacy of cytoflavin in the correction of functional state and working ability of Navy operators after a long working cycle. MATERIAL AND METHODS: Results of the examination of 25 Navy operators, aged from 27 to 42 years, were analyzed at baseline and after treatment with cytoflavin. The Rusalov questionnaire for Individuality Formal Dynamic Properties and EEG were used to evaluate the state of participants. RESULTS AND CONCLUSION: The results demonstrate the ability of cytoflavin to exert the positive effect on the energetic component of the functional state of Navy operators after a long working cycle, increasing the psychomotor activity and optimizing the spontaneous electrical activity of the brain. The activation of energetic potential, physical activity and emotional reactions by cytoflavin is correlated with the growth of the central nervous system reserves in Navy operators treated after a long working cycle.


Brain/drug effects , Flavin Mononucleotide/pharmacology , Inosine Diphosphate/pharmacology , Military Personnel , Neuroprotective Agents/pharmacology , Niacinamide/pharmacology , Psychomotor Performance/drug effects , Succinates/pharmacology , Adult , Brain/physiology , Drug Combinations , Exercise , Flavin Mononucleotide/administration & dosage , Humans , Inosine Diphosphate/administration & dosage , Male , Middle Aged , Neuroprotective Agents/administration & dosage , Niacinamide/administration & dosage , Succinates/administration & dosage , Surveys and Questionnaires
4.
Adv Gerontol ; 30(5): 757-764, 2017.
Article Ru | MEDLINE | ID: mdl-29322745

We conducted a study of 220 patients in polyclinic № 91 in St. Petersburg. It was revealed that elderly patients with osteochondrosis are characterized by a high prevalence and severity of osteochondrosis against the background of metabolic disorders in the structures of the spine. At the same time, the actual condition of the spine does not always determine the severity of the pain syndrome. The effect of osteochondrosis on the development of comorbid pathology has been clarified. The ways of correction of the clinical and psychophysiological status of elderly patients with osteochondrosis such as appointment of Cytoflavin, behavioral therapy and biofeed back therapy are suggested.


Spinal Osteochondrosis/psychology , Aged , Behavior Therapy , Drug Combinations , Flavin Mononucleotide/therapeutic use , Humans , Inosine Diphosphate/therapeutic use , Niacinamide/therapeutic use , Russia , Spinal Osteochondrosis/pathology , Spinal Osteochondrosis/therapy , Spine/pathology , Succinates/therapeutic use
5.
Zh Nevrol Psikhiatr Im S S Korsakova ; 116(11. Vyp. 2): 49-53, 2016.
Article Ru | MEDLINE | ID: mdl-28300813

AIM: To assess effects and to study an influence of cytoflavin on the changes of cognitive functions in the complex treatment of elderly patients with alcoholism. MATERIAL AND METHODS: A prospective cohort randomized parallel study was carried out in the group of 74 elderly patients with alcoholism. RESULTS AND CONCLUSION: Significant positive changes (p<0.05) in the clinical/neurological status of patients was observed during the optimized and combined treatment with the inclusion of cytoflavin in the treatment scheme. There was a rapid and marked improvement in the indices of neuropsychological tests compared to the patients of the comparison group.


Alcoholism/drug therapy , Cognition Disorders/drug therapy , Flavin Mononucleotide/therapeutic use , Inosine Diphosphate/therapeutic use , Neuroprotective Agents/therapeutic use , Niacinamide/therapeutic use , Succinates/therapeutic use , Aged , Alcoholism/complications , Cognition Disorders/etiology , Drug Combinations , Humans , Neuropsychological Tests , Prospective Studies
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